A biotech company in the US has been granted an ethical permission to perform a highly controversial study, using 20 brain dead patients. Ethical permission was granted by the Institutional Review Board in the US and India. This study is intended to stimulate the nervous system to activate the brain one more time. Bioquark hopes that its participation in ReAnima’s innovative project would be able to bring people back from the dead.
To note, so far there is no strong evidence of whether the project is realistic or impossible, but Dr. Calixto Machado is involved. He is a well-known neurological researcher of the American Academy of Neurology and he has written many papers that discuss about brain death.
The research team will perform several therapies on participants who have been medically declared brain dead. All participants live with the help of the life support machine. Scientists will play with stem cells and some chemicals. They will inject stem cells into the brain and also inject some chemicals into bone marrow. They will also involve nerve stimulation technique that has been proven to stimulate the nerves to be active again.
Once therapy completion has been administered, brain activity monitoring will be conducted over several months. Scientists will look for any signs of neurological reactivation, no matter how small it is. They will pay attention to the upper part of the spinal bone marrow. This section is the bottom of the brain responsible for the flow of cardiorespiratory function. Cardiorespiratory function is related to breathing and heartbeat.
According to Ira Pastor, CEO Bioquark Inc., the incorporation of biological means of regenerative medicine and medical devices is very necessary to perform complex initiatives. Medical devices used are common devices used to stimulate the central nervous system in patients with severe consciousness disorders. According to Pastor, the results may be known within the first 3 months.
For information, the central nervous system is bioelectrochemical, therefore using a neurotransmitter, a chemical, to perform the transport function of electrical signals throughout the body. Basically, this process is the process of sending an electric current in order to stimulate neurons.
This step is done on the premise that even in a coma, the neuron is capable of receiving electrical stimulation – but after the death of the brain, neurons begin to lose their ability, so the stimulus should be provided to foster the regeneration of neurons.
It is suspected that right when stem cells arrive, they are, under every condition, able to differentiate or morph into any cell in the human body. So far the scientists have got a great progress in the application of stem cells to repair damaged organs, such as the pancreas, liver, eyes, and even sensitive tissues such as brain tissue.
But we still see a difficult road to go into a condition where the stem cells can just be injected and then regenerating cells and new organs.
This is not an easy task!
This trial will start at the Anupam Hospital in Rudrapur, Uttarakhand in India, by providing cocktails of peptides to the brain dead patients. The peptides are chemicals that serve as the neuro transmitter. These chemicals will be combined with two weekly injections of stem cells. Pastor concludes that the project is a long term project that will bridge the amazing progress of treatment in humans.